Translational NeuroElectronics Lab
Designing and developing electronics to better understand the brain
PUBLICATIONS
Z. Zhao, H. Yu, D. J. Wisniewski, C. Cea, L. Ma, E. M. Trautmann, M. M. Churchland, J. N. Gelinas, D. Khodagholy, "Formation of anisotropic conducting interlayer for high-resolution epidermal electromyography using mixed-conducting particulate composite", Advanced Science, (2024) .pdf
L. Ma, D. J. Wisniewski, C. Cea, D. Khodagholy, J. N. Gelinas, "High-density, conformable conducting polymer-based implantable neural probes for the developing brain", Advanced Healthcare Materials, (2024) .pdf
O. J. Rauhala, L. Ma, D. J. Wisniewski, S. Shao, B. Schumacher, J. J. Ferrero, M. Kaspers, Z. Zhao, J. N. Gelinas, D. Khodagholy, "E-suture: mixed-conducting suture for medical devices", Advanced Healthcare Materials, (2024) .pdf
H. Yu, W. Kim, D. K. Park, J. H. Phi, B. C. Lim, J. Chae, S. Kim, K. J. Kim, F. A. Provenzano, D. Khodagholy, J. N. Gelinas, "Interaction of Interical Epileptiform Activity with Sleep Spindles is Associated with Cognitive Deficits and Adverse Surgical Outcome in Pediatric focal epilepsy", Epilepsia, (2024) .pdf
B. Sha, S. Zhao, M. Gu, D. Khodagholy, L. Wang, G. Q. Bi, Z. Du, "Doping-Induced Assembly Interface for Noninvasive in vivo Local and Systemic Immunomodulation", PNAS, (2023) .pdf
C. Cea, Z. Zhao, D. J. Wisniewski, G. D. Spyropoulos, A. Polyravas, J. N. Gelinas, D. Khodagholy, "Integrated Internal Ion-Gated Organic Electrochemical Transistors for Stand-Alone Conformable Bioelectronics", Nature Materials, (2023) .pdf
A. Armada-Moreira, A. M. Dar, Z. Zhao, C. Cea, J. N. Gelinas, M. Berggren, A. Costa, D. Khodagholy, E. Stavrinidou, "Plant Electrophysiology with Conformable Organic Electronics: Deciphering the Propagation of Venus Flytrap Action Potentials", Science Advances, (2023) .pdf
P. Dahal, O. J. Rauhala, D. Khodagholy, J. N. Gelinas, "Hippocampal–Cortical Coupling Differentiates Long-Term Memory Processes", PNAS, (2023) .pdf
D. Khodagholy, J. J. Ferrero, J. Park, Z. Zhao J. N. Gelinas, "Large-Scale, Closed-Loop Interrogation of Neural Circuits Underlying Cognition", Trends in Neurosciences, (2022) .pdf
A. R. Hassan, Z. Zhao, J. J. Ferrero, C. Cea, P. Jastrzebska‐Perfect, J. Myers, P. Asman, N. Firat Ince, G. McKhann, A. Viswanathan, S. A. Sheth, D. Khodagholy, J. N. Gelinas, "Translational Organic Neural Interface Devices at Single Neuron Resolution", Advanced Science, (2022) .pdf
A. N. Pouliopoulos, M. F. Murillo, R. Lynn Noel, A. J. Batts, R. Ji, N. Kwon, H. Yu, C. Tong, J. N. Gelinas, D. Khodagholy, S. A. Hussaini, E. E. Konofagou, "Non-invasive Optogenetics with Ultrasound-Mediated Gene Delivery and Red-light Excitation", Brain Stimulation (2022) .pdf
Z. Zhao, G. D. Spyropoulos, C. Cea, J. N. Gelinas, D. Khodagholy, "Ionic communication for implantable bioelectronics", Science Advances (2022) .pdf
D. R. Yao, H. Yu, O. J. Rauhala, C. Cea, Z. Zhao, Je. N. Gelinas, D. Khodagholy, "Anisotropic Ion Conducting Particulate Composites for Bioelectronics", Advanced Science, (2022), .pdf
S. Zokaei, M. Craighero, C.Cea, L. M. Kneissl, R. Kroon, D. Khodagholy, A. Lund, C. Müller, "Electrically Conducting Elastomeric Fibers with High Stretchability and Stability" Small, (2021) .pdf
M. S. Ejneby, M. Jakešová, J. Ferrero, L. Migliaccio, I. Sahalianov, Z. Zhao, M. Berggren D. Khodagholy, V Đerek, J.N. Gelinas E.D. Głowacki. "Chronic electrical stimulation of peripheral nerves via deep-red light transduced by an implanted organic photocapacitor." Nature Biomedical Engineering (2022).pdf
S. Dominguez, L. Ma, H. Yu, G. Pouchelon, C. Mayer, G.D. Spyropoulos, C. Cea, G. Buzsáki, G. Fishell, D. Khodagholy*, J.N. Gelinas*, "A transient postnatal quiescent period precedes emergence of mature cortical dynamics", eLife, (2021) .pdf
Z. Zhao, C Cea, J. N. Gelinas, D Khodagholy*, "Responsive manipulation of neural circuit pathology by fully implantable, front-end multiplexed embedded neuroelectronics", PNAS, Vol. 118, No. 20, (2021) .pdf Data
P. Jastrzebska-Perfect, S. Chowdhury, G.D. Spyropoulos, Z. Zhao, C. Cea, J.N. Gelinas*, D. Khodagholy*, “Translational neuroelectronics”, Advanced Functional Materials, 1909165 (2020) .pdf
P. Jastrzebska-Perfect, G.D. Spyropoulos, C. Cea, Z. Zhao, O.J. Rauhala, A. Viswanathan, S.A. Sheth, J.N. Gelinas*, D. Khodagholy*, “Mixed-conducting particulate composites for soft electronics”, Science Advances, Vol. 6, No. 17, eaaz6767, (2020) .pdf Video
C. Cea, G.D. Spyropoulos, P. Jastrzebska-Perfect, J.N. Gelinas*, D. Khodagholy* “Enhancement mode ion-based transistor – comprehensive interface for in vivo electrophysiology”, Nature Materials, (2020) .pdf Video
G.D. Spyropoulos, J. Savarin, E. Gomez, D. Simon, M. Berggren, J.N. Gelinas, E. Stavrinidou*, D. Khodagholy*, “Transcranial electrical stimulation and recording of brain activity using freestanding plant-based conducting polymer hydrogel composites”, Advanced Materials Technologies, 1900652, (2019) .pdf
O.J. Rauhala, S. Dominguez, G. Spyropoulos, J. Ferrero-Lopez, T. Boyers, P. Jastrzebska-Perfect, C. Cea, Z. Zhao, D. Khodagholy*, J.N. Gelinas*, “Chitosan-based, biocompatible, solution processible films for in vivo localization of neural interface devices”, Advanced Materials Technologies, 1900663, (2019) .pdf
P. Dahal, N. Ghani, A. Flinker, P. Dugan, D. Friedman, W. Doyle, O. Devinsky, D. Khodagholy*, J.N. Gelinas*, "Interictal epileptiform discharges shape large-scale intercortical communication", Brain, 0:awz269, (2019) .pdf
G.D. Spyropoulos, J.N. Gelinas*, D. Khodagholy*, "Internal-ion gated organic electrochemical transistor: a building block for integrated bioelectronics", Science Advances, Vol. 5, No. 2 (2019) .pdf
K. Tybrandt*, D. Khodagholy*, B. Deichler, F. Stauffer, A. Renz, G. Buzsáki, J. Vörös, "High-Density Stretchable Electrode Grids for Chronic Neural Recording" Advanced Materials, 30,1706520 (2018) .pdf
D. Khodagholy*, J. N. Gelinas* and G. Buzsáki “Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus” Science,Vol. 358, Issue 6361, pp. 369-372 ,(2017) .pdf
I. Uguz, C. M Proctor, V. F Curto, A. Pappa, M. J Donahue, M. Ferro, R. M Owens, D. Khodagholy, S. Inal, G. G Malliaras, “A Microfluidic Ion Pump for In Vivo Drug Delivery”, Advanced Materials, Adv. Mater. 29- 27- 1701217, (2017) .pdf
D. Khodagholy, J. N. Gelinas, Z. Zhao, M. Yeh, M. Long, J D. Greenlee, W. Doyle, O. Devinsky , and G. Buzsáki, “Organic electronics for high-resolution electrocorticography of the human brain” Science Advances, 2, e1601027 (2016) .pdf
A. Jonsson, S. Inal, l. Uguz, A. J. Williamson, L. Kergoat, J. Rivnay, D. Khodagholy, M. Berggren, C. Bernard, G. G. Malliaras, D. T. Simon, "Bioelectronic neural pixel: Chemical stimulation and electrical sensing at the same site", Proc. Natl. Acad. Sci. , 201604231 (2016) .pdf
J. N. Gelinas, D. Khodagholy, T. Thesen, W. Doyle, O. Devinsky, G. Malliaras and G. Buzsáki, “Interictal epileptiform discharges induce hippocampal-cortical coupling”, Nature Med, doi:10.1038/nm.4084, (2016) .pdf
D. Khodagholy, J. Gelinas, T. Thesen, W. Doyle, O. Devinsky, G. Malliaras and G. Buzsáki, “NeuroGrid: recording action potentials from the surface of the brain”, Nature Neuro. DIO: 10.1038/nn.3905, (2015) .pdf
G. Buzsáki, E. Stark, A. Berényi, D. Khodagholy, D. Kipke, E. Yoon and Kensall Wise, “Tools for probing local circuits: high-density silicon probes combined with optogenetics”, Neuron, (2015) .pdf
J. Rivnay, P. Leleux, M. Ferro, M. Sessolo, A. Williamson, D Khodagholy, Marc Ramuz, X. Strakosas, R. Owens, C. Benar, J. Badier, C. Bernard, and G.G. Malliaras, “High-performance transistors for bioelectronics through tuning of channel thickness", Science Adv., (2015) .pdf
J. Rivnay, P. Leleux, M. Sessolo, D. Khodagholy, T. Herve, M. Fiocchi, and G. G. Malliaras, “Organic Electrochemical Transistors with Maximum Transconductance at Zero Gate Bias” Adv. Mater., 25, 48, 7010-4, (2013) .pdf
D. Khodagholy, J. Rivnay, M. Sessolo, M. Gurfinkel, E. Stavrinidou, P. Leleux, T. Herve, S. Sanaur, and G.G. Malliaras, “High transconductance organic electrochemical transistor”, Nature Comm. 4, 2133, (2013) .pdf
E. Stavrinidou, P. Leleux, H. Rajaona, D. Khodagholy, J. Rivnay, M. Lindau, S. Sanaur, and G. G. Malliaras, “Direct measurement of ion mobility in a conducting polymer”, Adv. Mater, 25, 32, 4488–4493, (2013) .pdf
M. Sessolo*, D. Khodagholy*, J. Rivnay, F. Maddalena, M. Gleyzes, E. Steidl, B. Buisson and G. G. Malliaras, “Easy-to-Fabricate Conducting Polymer Microelectrode Arrays”, Adv. Mater., 25, 15, 2135–2139, (2013) .pdf
D. Khodagholy, T. Doublet, M. Gurfinkel, P. Leleux, P. Quilichini, A. Ghestem, E. Ismailova, T. Herve, S. Sanaur, C. Bernard and G. G. Malliaras, “In vivo recordings of brain activity using organic transistors”, Nature comm., 4, 1575, (2013) .pdf
L. H. Jimison, S. A. Tria, D. Khodagholy, M. Gurfinkel, E. Lanzarini, A. Hama. G. G. Malliaras, R. M. Owens, “Measurement of Barrier Tissue integrity with an organic electrochemical transistor”, Adv. Mater, 24, 44, 5919–5923, (2012) .pdf
L. H. Jimison, A. Hama, X. Strakosas, V. Armelb, D. Khodagholy, E. Ismailova, B. Winther-Jensenb, and R. M. Owens, “PEDOT:TOS with PEG: A biofunctional surface with improved electronic characteristics” J. Mater. Chem., 2012,22, 19498-19505 (2012) .pdf
E. Ismailova, T. Doublet, D. Khodagholy, P. Quilichini, A. Ghestem, S.Y. Yang, C. Bernard, and G.G. Malliaras, "Plastic neuronal probes for implantation in cortical and subcortical areas of the rat brain", Int. J. Nanotechnology, 9, 517 (2012) .pdf
D. Khodagholy, V.F. Curto, K. J. Fraser, M. Gurfinkel, R. Byrne, D. Diamond, G. G. Malliaras, F. Benito-Lopez, and R. M. Owens, “Organic electrochemical transistor incorporating an ionogel as solid state electrolyte for lactate sensing”, J. Mater. Chem., 22, 4440-4443 (2011) .pdf
K. Fraser, V. Curto, Sh. Coyle, B. Schazman, R. Byrne, F. Benito-Lopez, Fernando, D. Khodagholy , R. Owens, G. G. Malliaras D. Diamond “Electrochemical transistors with ionic liquids for enzymatic sensing”, SPIE Proc. , doi:10.1117/12.894412 (2011) .pdf
D. Khodagholy, M. Gurfinkel, E. Stavrinidou, P. Leleux, T. Herve, S. Sanaur, and G.G. Malliaras, "High speed and high density organic electrochemical transistor arrays", Appl. Phys. Lett. 99, 163304 (2011) .pdf
D. Khodagholy, T. Doublet, M. Gurfinkel, P. Quilichini, E. Ismailova, P. Leleux, T. Herve, S. Sanaur, C. Bernard, and G.G. Malliaras, “Highly conformable conducting polymer electrodes for in vivo recordings”, Adv. Mater. 36, H268 (2011) .pdf